Organic Chemicals

6(5H)-Phenanthridone

  • CAS:1015-89-0
  • purity:99%
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What is the 6(5H)-Phenanthridone ?

6(5H)-Phenanthridone is , while it's Molecular Formula is C13H9NO. 6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.

What is the CAS number for 6(5H)-Phenanthridone ?

The CAS number of 6(5H)-Phenanthridone is 1015-89-0.

More information of 6(5H)-Phenanthridone 1015-89-0 are:

Synonyms

5H-Phenanthridin-6-one;6-Phenanthridinol;6-Phenanthridinone;6-Phenanthridone;NSC 11021;NSC 40943;NSC 61083;PJ 97A;WD 99-004344;

CAS?Number

1015-89-0

Molecular Formula

C13H9NO

Molecular Weight

195.221

Density

1.231 g/cm3

Melting Point

290-292 °C(lit.)

Boiling Point

274.843 °C at 760 mmHg

Flash Point

158.663 °C

HS CODE

29337900

PSA

32.86000

LogP

2.68130

Pka

13.27±0.20(Predicted)

What is 6(5H)-Phenanthridone (1015-89-0) used for?

6(5H)-Phenanthridinone, also known as 6-Phenanthridone, is a member of the phenanthridine class with an oxo substituent at position 6. It is a potent poly(ADP-ribose) polymerase (PARP) inhibitor that exhibits immunosuppressive activity. 6(5H)-Phenanthridone has been extensively studied for its role in cellular response to irradiation and its potential applications in various fields.

InChI:InChI=1/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15)

Articles related to 6(5H)-Phenanthridone:

Article

Source

MeOTf- and TBD-Mediated Carbonylation of ortho-Arylanilines with CO2 Leading to Phenanthridinones

Wang, Sheng,Shao, Peng,Du, Gaixia,Xi, Chanjuan

, p. 6672 - 6676 (2016)

-

Akermark et al.

, p. 1365 (1975)

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